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Schwabe News Volume 2 | Issue 1 | February 2011

Grindelia Pentarkan (Tablets)

Indications: Mild bronchial asthma and allergic bronchitis.

Introduction

Asthma is a chronic disease characterised by airway inflammation and increased responsiveness of the tracheobronchial tree to diverse stimuli that result in varying degrees of airway obstruction. Recurrent attacks of wheezing, coughing, chest tightness, and dyspnoea (shortness of breath) are symptomatic. Severity ranges from intermittent and mild complaints to continuous and disabling respiratory symptoms, despite intensive therapy.

Bronchial asthma is usually intrinsic (no cause can be demonstrated), but is occasionally caused by specific allergies (such as allergies to mould, dust, pollen). Symptoms can occur spontaneously, or be triggered by respiratory infections, exercise, cold air, tobacco smoke or other pollutants. Pathological features of this inflammatory, allergic reaction within the bronchial wall include the presence of spasm, exudation (mucus production) and oedema. Treatment is aimed at avoiding known allergens. Symptoms of mild bronchial asthma can be controlled by Grindelia Pentarkan® (WSI). Acute and severe asthma may require special medication and hospitalisation.

Composition: Each tablet of 250mg contains: Ephedra vulgaris 1x 75mg, Grindelia robusta 1x 75mg, Ipecacuanha 3x 25mg, Justicia adhatoda 1x 25mg, Lobelia inflata 3x 25mg, Excipients Q.S.

Indications of individual ingredients

Ephedra vulgaris acts on the mucous membranes of the bronchi. It has proved to be of value for decongestion, relaxation and expectoration.

Grindelia robusta is indicated for bronchial asthma and chronic bronchitis. It is a remedy for wheezing, oppression of the chest with viscous mucus which is difficult to detach, dyspnoea.

Ipecacuanha is indicated for spasmodic cough, bronchial asthma, and dyspnoea. Its action covers coughing with nausea and vomiting, constant constriction in the chest, attacks of difficult breathing, incessant cough with every breath, bubbling rales, coryza and whooping cough.

Justicia adhatoda alleviates many diseases of the respiratory tract. It acts on dry cough, coughing with sneezing and tightness across the chest, paroxysmal cough, asthmatic attacks, and cough with severe dyspnoea.

Lobelia inflata is indicated for asthma with spasmodic cough and dyspnoea from constriction of the chest exacerbated by any exertion. It is useful during acute attacks of bronchial asthma accompanied by nausea, vomiting and sweating.

Dosage: 2 tablets should be taken 3 times a day. Children between 6-12 years of age should be given half of the adult dose. Side effects: No side effects of Grindelia Pentarkan®  (WSI) are known. Contra-indications: This product should be used under medical advice and supervision in children under 6 years of age. Interactions: No interactions between Grindelia Pentarkan®  (WSI) and other products are known. Presentation: Bottle of 20gm.

Reference: Grindelia Pentarkan product leaflet