Gelsemium sempervirens MT centers its action upon the nervous system, causing various degrees of motor paralysis. It is used in cases of dizziness, drowsiness, dullness and trembling. Paralysis of various groups of muscles about the eyes, throat, chest, larynx, sphincter, extremities etc. It is also used in general depression from heat of sun. Nervous affections of cigarmakers. Herbal use in whooping cough, asthma, migraine and insomnia should be under medical supervision. The results of a recent study reflected that methanolic extract of this drug decreased locomotor activity, produced muscle relaxation and showed antianxiety activity, substantiating the traditional use. Many studies have established its homoeopathic use on anxiolytic, analgesic, behavioural effects, emotional responses, diminution of thigmotaxis (poor response to touch) or neophobia, and immunotrope effect on the cellular (granulocytes, monocytes, total lymphocytes, TCD4+, TCD8+ and NK cells) and humoral (immunoglobulins A, E and G) immunity in anxious mice.
1. W. Boericke, New Manual of Homoeopathic Materia Medica & Repertory [with Relationship of Remedies], Second Re-Augmented & Revised Edition Based on Ninth Edition, Reprint Edition 2002, B. Jain Publishers, New Delhi.
2. Dr. P. N. Varma, et al., A Compendium of Rare and Clinically Established Mother Tinctures, 4th Edition, Dr. Willmar Schwabe India Pvt. Ltd., A-36, Sector 60, Noida.