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Biocombination No. 12

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Headache • Used in the management of headaches.

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20 g, 550 g

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Indications: Headaches due to congestion and a rush of blood to the head, neuralgia. Better from heat, worse from cold. Nervousness as a consequence of worries, sleeplessness or a low-functioning liver. Worse in the evening or in a warm room, better in the open air.


It is a common symptom of many disorders frequently complained but in most of the cases it is transient, temporary and of trivial importance. In number of cases it is associated with serious organic disease and such cases need to be differentially understood.

1. Headache is often complained in tension and anxiety states, nervousness, sleeplessness, liver complaints, and indigestion. Bioplasgen/Biocombination – 12 is very effective in such cases.

2. It also occurs as a result of toxaemia in acute infection especially typhoid fever and influenza where this drug has to be given along with the medicine for the cause.

3. Headache is also caused due to anaemia, alcoholism (hangovers), hypertension, eyestrain, nasal catarrh or sinusitis. Bioplasgen/Biocombination 12 is also effective in such cases.

4. Headache due to local lesions in the brain, cerebral problems including tumours, abscesses or meningitis will need specialised medical care. Bioplasgen/Biocombination 12 is helpful as associated medicine.

Composition: Ferrum phosphoricum 3x, Kalium phosphoricum 3x, Mangnesia phosphorica 3x, and Natrum muriaticum 3x in equal proportion.

Proven indications of the ingredients within the claimed sphere of action :

Ferrum phosphoricum: Itis indicated for congestive headaches in inflammatory and febrile conditions and, in anaemic headaches. It covers headaches due to sun heat, throbbing pains or vertigo. Headache is better on cold application.

Kalium phosphoricum: Itis indicated for headaches due to anxiety, stress, tension, worry, sleeplessness, and excessive mental and physical exertion, It is especially suited for occipital headaches better, after rising, cerebral anaemia, vertigo and headache with weary empty gone feeling at the stomach.

Magnesium phosphoricum: Itis indicated for neuralgic and spasmodic pains where relief is felt by warmth. Headache with vertigo is better walking open air with the sensation as if the liquid is filled and the brain is changing position.

Natrum muriaticum: Itis indicated for throbbing blinding headache as if many hammers were knocking on the brain worse in the morning, after menses. It is also indicated for the anaemic headaches of school children, nervous, discouraged and broken down. Useful in semi-lateral congestive sunrise to sunset headache in anaemic with complaints of nausea, vomiting, eye strain and frontal sinus inflammations.

Contra-indication: Nil. It is a safe, non-toxic drug with no side effects.

Dosage: Adults 4 tablets, children 2 tablets, at a time, four times a day at intervals of three hours. In acute conditions, 5 tablets every 15-minute with a little warm water.

Presentation: Tablets of 100 mg in bottles of 20g.

Alcohol: There is no reported safety concern if it is taken with alcohol.

Pregnancy: It is safe to take during pregnancy.

Driving: It is safe to use during driving.

Breastfeeding/Lactation: It can be used while breastfeeding.

Kidney: There is no known contraindication with kidney diseases.

Sugar: It does not affect blood sugar levels.

Immunity: It will not affect the immunity of an individual.

Liver: It is safe for the liver.

High blood pressure/Hypertension: It is safe to use in patients with hypertension.

Low blood pressure: It will not lower the blood pressure.

Heart: It does not contain any ingredient which will affect the heart.

Mentally retarded: There is no known contraindication with mentally retarded persons.

Post covid impacts: There is no known contraindication with post covid impacts.

Diarrhea: It will not cause any diarrhea.

Gastric: There are no known effects on the gastrointestinal system.

Empty stomach: It is preferably to be taken after a meal.

Skin allergy: There is no skin allergy when using Biocombination No.12. 

Habit: It is not a habit-forming product.

Overdose: In case of overdose, drink lots of water or consult a physician.

Storage: It has to be stored in a cool dark place, away from sunlight and strong-smelling substances.

Temperature: The temperature should be 25 degrees centigrade.


Biocombination No.12 is a special biochemic combination consisting of Ferrum phosphoricum, Kali phosphoricum, Magnesium phosphoricum, and Natrum muriaticum in equal proportions. It is formulated for the management of headaches.

Yes, it is suitable for children.

It has to be taken as long as the symptoms are better or till the improvement sets in or as prescribed by the physician.

Yes, it is safe to take Biocombination No.12.

No, it does not cause any dryness in the mouth.

Biocombination No.12 is used in the management of headaches caused due to congestion, a rush of blood to the head, neuralgia, nervousness due to constant worries, depression, sleeplessness, or a low-functioning liver. Headaches from tension, anxiety, stress, nervousness, sleeplessness, liver complaints, and indigestion. It is also effective in headaches due to anemia, alcoholism, hypertension, eyestrain, nasal catarrh, sinusitis, local lesions of the brain, cerebral tumors, abscesses, or meningitis.

It should be taken as 4 tablets for adults, and 2 tablets for children, at a time, four times a day at intervals of three hours or as otherwise prescribed by the physician.

Biocombination No.12 is the combination of important homeopathic medicines such as Ferrum phosphoricum, Kali phosphoricum, Magnesium phosphoricum, and Natrum muriaticum. Ferrum phosphoricum is indicated in headaches where the head feels sore to touch, cold, from noise and jar, a rush of blood to the head, ill effects of sun-heat, throbbing sensation, vertigo, and better from cold applications. Kali phosphoricum is indicated in occipital headache, better after rising, vertigo from lying, standing up, from sitting, and when looking upwards, cerebral anemia, the headache of students who are worn out by fatigue, relieved by gentle motion, weary empty gone feeling at the stomach.
Magnesium phosphoricum is indicated in headaches after mental labor with chilliness always better warmth, vertigo on moving falls forward on closing eyes, better walking in open air, and sensation as if contents were liquid as if parts of the brain were changing places. Natrum muriaticum is indicated in blinding headaches, as if a thousand little hammers were knocking on the brain, in the morning on awakening, after menstruation, from sunrise to sunset, throbbing in nature, and anaemic headaches of school girls who are nervous, discouraged and broken down. The headache is chronic in nature, semi-lateral, congestive, from sunrise to sunset, with a pale face, nausea, vomiting, periodical, from eye strain, menstrual accompanied by numbness and tingling in lips, tongue, and nose relieved by sleep. The frontal sinus is inflamed.

No side effects have been reported so far.

It is not a problem if you skip a few doses, but don’t take double doses.

Ferrum phosphoricum, Magnesium phosphoricum, Alpha-SH, Natrum muriaticum.

Each tablet of Biocombination No.12 contains Ferrum phosphoricum 3X 25mg, Kali phosphoricum 3X 25 mg, Magnesia phosphorica 3X 25 mg, and Natrum muriaticum 3X 25mg.

Manufactured in India by Dr. Willmar Schwabe India Pvt. Ltd. A-36, Sector-60, Uttar Pradesh, Noida – 201304. Country of Origin: India. Registered office Address: Dr. Willmar Schwabe India Pvt. Ltd. H-36, Green Park Extension, New Delhi, Pin: 110016. Expiry: 5 years for the date of manufacturing.


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