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Guatteria gaumeri – Schwabe News Apr – Dec 2019 – Schwabe India

Guatteria gaumeri 


Guatteria gaumeri is a 10 to 15 m tall tree, with a blackish coloured bark. Its leaves are oval-lanceolate, acuminate, dark green about 9 to 11 cm long. The fruit is a round cluster approximately 2 cm in diameter, with a very disagreeable taste and odour.

GUATTERIA GAUMERI

A homoeopathic mother tincture is prepared from dried bark of the plant. It is covered by Homoeopathic Pharmacopoeia of United States.

It contains alpha-asarone as a primary constituent. 

Guatteria gaumeri acts on the liver and gallbladder, kidney and pancreas. It has affinity to improve digestive complaints with liver and biliary manifestation. It is one of the frequently used homoeopathic remedy for liver complaints. It is reported for gallstone. Its anti hypercholesterolemic effect was reported way back in 1982. Studies have found that this is primarily due to its main component Alpha-asarone by decreasing the secretion of lipids. It is also found to be non-toxic.  A clinical study has shown decrease in TC, LDL, VLDL, and increase in HDL.

Recommended dose: 1x/Q, 10-20 drops.


References: 

  1. Josefina Sanchez, Resendiz Angel, Lerdo de Tejada, Cholesterol-lowering effect of Guatteria gaumeri (preliminary report). Journal of Ethnopharmacology
  2. Volume 6, Issue 2, September 1982, Pages 239-242
  3. L.Rodríguez-Páez, M.Juárez-Sanchez, J.Antúnez-Solís, I.Baezaa C.Wong, α-Asarone inhibits HMG-CoA reductase, lowers serum LDL-cholesterol levels and reduces biliary CSI in hypercholesterolemic rats. Phytomedicine, Volume 10, Issue 5, 2003, Pages 397-404
  4. P.Morales-Ramírez, E.Madrigal-Bujaidar, J.Mercader-Martínez, M.Cassani, G.González, G.Chamorro-Cevallos, M.Salazar-Jacobo, Sister-chromatid exchange induction produced by in vivo and in vitro exposure to alpha-asarone. Mutation Research/Genetic Toxicology, Volume 279, Issue 4, 16 June 1992, Pages 269-273
  5. Aejaz Husain, Ashish Indani, Poonam Bhutada. Hypercholesterolemia effectively managed with homeopathic medicine Gautteria gaumeri (Yumel): results from a clinical study in academic clinical set up in north India. Int J Adv Med. 2017 Jun;4(3):772-777
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