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Volume 6 & 7 | Issues 10-12 (6) & 1-3 (7) | Oct 2015 - Mar 2016 | 2016-04-13

Schwabe news

Schwabe News

Volume 6 & 7 | Issues 10-12 (6) & 1-3 (7) | Oct 2015 - Mar 2016

Editorial Advisor: Dr. P. N. Varma | Editor: Dr. R. Valavan

 

Contents

  • Editorial

 

  • Current News
  • CME program at Lucknow by Schwabe India
  • Schwabe India Awarded India’s Most Promising Brand
  • Schwabe India Managing Director conferred National Industrial Excellence Award
  • Schwabe India’s Participation in India International Trade Fair 2015
  • Visit of students to Schwabe India

 

  • Proving
  • Tribulus terrestris
  • Theridion

 

  • Mother tincture info
  • Syzgium jambolanum
  • Lupulus

 

  • Product watch
  • Dr. Willmar Schwabe’s Alfalfa Tonic®
  • Essentia Aurea Gold - Drops

 

  • Research news
  • Protective effect of Gymnema sylvestre L. against advanced glycation end-product, sorbitol accumulation and aldose reductase activity in Homoeopathic Formulation
  • Homoeopathic drug standardization through biological evaluations: An untrodden avenue
  • Immunological models in high dilution research following M Bastide


 

Editorial

Schwabe India has been active in conducting CME programs in the last few years. CMEs conducted in the last few months have been reported in previous issues. The recent program was organised in Lucknow with eminent homoeopaths like Dr. V. K. Vimal, Principal, National Homoeopathic Medical College, Lucknow, as the chief guest, Dr. V. Prasad, Director, UP, as Guest of Honour and Dr. Girish Gupta, Gaurang Clinic & Centre for Homoeopathic Research, as the chief speaker. The details have been reported under current news along with awards and recognition received by Schwabe India and its managing director, Schwabe India’s participation in IITF and student visits.

 

Less known drugs like Tribulus terrestris and Theridion have been reported under provings. A common thread in in these drugs is that both the drugs are good where nervous weakness is found. While the former is more inclined to the genito-urinary sphere, the latter is more useful in central nervous system. We hope that it will help to use these drugs with wider clinical applications.

 

 

Under mother tincture Syzygium jambolanum, a well-known drug for diabetes, is covered. There are many scientific studies on its anti-diabetic activity. Lupulus, another drug covered under this section, has been recommended in literature for nervous conditions.

 

Alfalfa Tonic is one of the oldest products in the field of homoeopathy. Though there are many products available in the market today, Schwabe’s Alfalfa Tonic is one of the oldest formulations. Same is true with Schwabe’s Essentia Aurea Gold Drops. Scientific information of these products is given under product watch.

 

Research news covers good number of recent publications on Gymnema sylvestre, standardisation of high dilutions and immunological models of high dilutions.

 

Hope you will find this issue informative. You may drop in your feedback here: https://www.schwabeindia.com/contact-us

 

Thank you

 

Dr. R. Valavan, BHMS, MD (Hom), MBA

Editor

 

 

 


Current news

CME program organised by Schwabe India in Lucknow

Schwabe India has conducted a CME in Lucknow on 27th December 2015. The chief guest was Dr. V. K. Vimal, Principal, National Homoeopathic Medical College, Lucknow. Dr. V. Prasad, Director, UP, had graced occasion as Guest of Honour. It was a well-packed auditorium at hotel The Piccadily. Homoeopaths from across the state had attended the program. The speaker Dr. Girish Gupta had delivered an interesting lecture on polycystic ovarian disease. He had presented different cases handled with different remedies.

 

Schwabe India Awarded India’s Most Promising Brand

Schwabe India has been excelling in many aspects in the last few years. It has been awarded by various organisations for its services to the society. In the last two years, it has been awarded the Quality Brand India 2015-17 and Alternative Brand of the year 2014 at the India Health and Wellness Summit and Awards 2014. Recently, London based World Consulting & Research Corporation has conducted an in-depth research on the India’s Brands - 2015, and awarded Schwabe India as one of the Most Promising Brand for the Year 2014-2015 in Health Care Category considering the growth over the past few years, huge impact on the minds of consumers, etc.

 

Schwabe India Managing Director conferred National Industrial Excellence Award

Mr. Ashish Kumar, the Managing Director of Schwabe India, has been conferred National Industrial Excellence Award by National Chamber of Commerce and Industry of India at 3rd National Seminar on National Economic Growth Through Individual Contribution.

 

 

Schwabe India’s Participation in India International Trade Fair 2015

Schwabe India is keen to participate in events of international and national importance like India International Trade Fair, German Fair, Arogya, The Indian Science Festival, etc. in order to spread the awareness of homoeopathy.

Visit of students to Schwabe India

Year on year, academic and professional visitors to Schwabe India has been growing. In the last quarter of 2015 and first quarter of 2016 has attracted around 2000 students and faculty members from across the country. 

 

Proving

Tribulus terrestris

It is a drug used in Indian system of medicine since long. Botanically known as Tribulus langinosus Linn., it is called in Hindi as Gokhru. Though the drug has been reported by W. Boericke, R. Murphy, P. N. Varma, etc.. recently this drug has been proved by Central Council for Research in Homoeopathy, Government of India. The proving details are in the book “Homoeopathic Drug Provings”, published by the council in 2005. The proving was conducted in 1996–97 using mother tincture and 30 centesimal potencies at (i) Drug Proving Research Unit, Ghaziabad (U.P.) and (ii) Drug Proving Research Unit, Midnapore (W.B.). 15 provers in the age group of 18-45 years took part in the proving.  5 of them were females. Below is the updated materia medica of old literature with new proving.

 

It is a drug useful in urinary affections, especially dysuria, and in debilitated states of the sexual organs, as expressed in seminal weakness, ready emissions and impoverished semen.

Mind

Angry on contradiction.

Vertigo

Dizziness and tendency to fall, with trembling sensation, vanishing of thoughts and flushing of face, lasting for half an hour.

Head

Throbbing headache extending from right orbit to nape of neck, worse afternoon, after 2 p.m.; better pressure.

Eyes

Swelling in eyelids with agglutination in morning and bland watery discharge. 

Nose

Fluent coryza with constant discharge in drops.  Bland watery discharge turns to sticky and thick followed by short cough.

Throat

Constant pain in throat with dysphagia, worse morning, evening; better warm drinks.  Pain in tonsils, worse by swallowing.

Stomach

Desire for smoking.  Heaviness in lower abdomen with loss of appetite and thirstlessness.

Rectum

Urge for stool after eating.  Loose watery stool, greenish, worse early morning.  Stool loose, yellowish, offensive, 3-4 times a day. Constipation: no urge for stool, stool scanty, semisolid, mucoid with after much straining and sensation of heaviness of abdomen.

Male

Prostatitis and sexual neurasthenia. It meets the auto-traumatism of masturbation correcting the emissions and spermatorrhoea. Partial impotence caused by overindulgence of advancing age, or when accompanied by urinary symptoms, incontinence, painful micturition, etc.

Urinary

Burning pain during urination, worse morning. Calculous affections.

Respiratory

Spasmodic, dry cough, worse night.

Back

Cramping pain in back, worse morning, night, evening, bending forward; better at noon, lying down.

Extremities

Pain in legs, calf muscles, worse sitting; better walking, pressure.  Pain in knee joints, worse morning, night; better pressure.

Fever

Dry heat with throbbing headache, thirstlessness, poor appetite and weakness.  Dry heat with headache, nasal discharge, bitter taste and short dry cough.  Fever with uneasiness, worse afternoon.

Skin

Burning pain all over the body, better open air. Maculo-papular, blackish eruptions over thigh with burning pain, worse night, touch.  Itching inside the thighs, worse scratching followed by burning, night, open air. Papular eruptions with itching between thighs.

Reference:

  1. Homoeopathic Drug Provings, Central Council for Research in Homoeopathy, 61-65, Institutional Area, Opp. ‘D’ Block, Jankpuri, New Delhi, First Edition, 2005
  2. P. N. Varma, Indu Vaid, Encyclopaedia of Homoeopathic Pharmacopoeia, Updated edition 2007, B. Jain Publishers, New Delhi.
  3. W. Boericke, New Manual of Homoeopathic Materia Medica & Repertory [with Relationship of Remedies], Second Re-Augmented & Revised Edition Based on Ninth Edition, Reprint Edition 2002, B. Jain Publishers, New Delhi.
  4. R. Murphy, Homeopathic Remedy Guide, Lotus Health Institute, Stuart, Virginia, United States.
  5. R. Murphy, Homeopathic Clinical Repertory, Lotus Health Institute, Stuart, Virginia, United States.
  6. R. Murphy, Homeopathic Remedy Guide, RadarOpus 1.33 (Homoeopathic Software), Archibel S.A. Rue Fontaine St. Pierre 1E, Zoning Industriel de la Fagne, 5330 Assesse, Belgium.
  7. F. Schroyens, Synthesis Treasure Edition 2009V, RadarOpus 1.33 (Homoeopathic Software), Archibel S.A. Rue Fontaine St. Pierre 1E, Zoning Industriel de la Fagne, 5330 Assesse, Belgium.

 

Theridion

Theridion curassavicum Walk. is the scientific name of Black spider of Curacoa. This drug finds mention in literatures with limited data. A new proving by Central Council for Research in Homoeopathy, India, has established many new symptoms. The proving details are in the book “Homoeopathic Drug Provings”, published by the council in 2005. The drug has earlier been reported by T. F. Allen, W. Boericke, J. H. Clarke and others. Mother tincture of this drug is prepared from the entire spider. The proving was conducted in 1991-92 suing 30 and 200 centesimal potencies at (i) Drug Proving Research Unit, Ghaziabad (U.P.), and (ii) Homoeopathic Drug Research Institute, Lucknow (U.P.).  28 provers in the age group of 18-41 years took part in the proving.  7 of them were females. Below is the updated materia medica of old literature with new proving.

 

It covers nervous hyperaesthesia, vertigo, sick headache, peculiar pain around heart region, phthisis florida, scrofula. It has affinity for the tubercular diathesis.

 

Mind

Restless; finds pleasure in nothing. Time passes too quickly. Mood; angry and quarrelsome.  Improved concentration while reading.

Head

Pain worse anyone walking over floor. Vertigo, with nausea and vomiting on least motion, particularly when closing eyes. Throbbing pain in whole head with aversion to talk and poor appetite, worse 1.30-4.30 p.m., talking.  Bursting pain and lightness in temples and forehead, with puffiness of upper eyelids, better tight bandaging, sleep.

Eyes

Luminous vibrations before eyes; sensitive to light. Pressure behind eyeballs. Throbbing over left eye. Heaviness of eyes with aversion to work, worse straining, pressure; better rest.  Heaviness in left eye, worse on waking.  Profuse bland lachrymation from both eyes, worse open air, morning. Lachrymation bland as if due to a foreign body, worse after watching television, after studies. Thick, white discharge from left eye, worse evening. Itching in eyes, inclination to wink and wipe eyes frequently, worse morning, night; better washing with cold water.  Stitching pain with swelling in left lower eyelid.  Stye on left lower eyelid with redness and exudation, better warm application. Haziness of vision.  Darkness in front of eyes.  Difficulty in viewing distant objects, worse sunlight.

Nose

Discharge yellowish, thick, offensive; ozæna (Puls; Thuja). Coryza with profuse nasal discharge, lachrymation with difficulty in breathing, worse leaning forward, open air.  Coryza with fluent discharge worse at night.  Coryza with cough, better lying down.  Nasal discharge, thin with sneezing, worse warm drinks; better bathing.  Nose obstructed, worse morning.

Face

Painful and pustular pimples, on cheek near left eye, worse touch.

Mouth

Dryness of mouth with thirst, worse night.

Throat

Stitching pain in throat, worse night, eating, swallowing liquids.  Irritation in throat with splinter like sensation and sneezing.

Abdomen

Intermittent griping pain, in left hypochondrium, worse movement; better sitting.  Griping pain around umbilical region, worse pressure.  Pain in abdomen and joints of legs, worse movement.

Rectum

Loose, watery stool, worse midnight.

Urinary

Copious, frequent urination, with thirst, worse night.

Female

Thin white leucorrhoea, with dimness of vision.

Respiratory

Dry, spasmodic cough with rawness in throat and watery nasal discharge, worse cold water, uncovering, midnight, morning; better warmth, covering. Violent, spasmodic cough with wheezing and pain in left side of chest.  Cough with expectoration, better lying down.  Expectoration, tenacious yellowish green, worse at night.

Back

Tenderness in left lumbar region, worse pressure, movement; better bending forward.

Extremities

Pain in popliteal region, as from a boil.  Aching pain in thighs with sweating on uncovered parts.  Cramping pain in both legs, worse evening; better hard pressure, massaging.

Dreams

Dreams of robbers, wakes up with fear.  Dreams of accident from electric shock.  Dreams of past events of childhood.

Fever

Mild fever with chill and weakness in whole body with anorexia, bitter taste, frequent scanty urination, worse midnight; better covering.  Fever in the morning with chill and bursting headache.

Skin

Papular eruption on chest, of size of a mustard seed, reddish, hard.  Gram size crusty, pustular boil in right inguinal region with throbbing pain, worse movement, pressure; better rest. Small pustule on pubis, worse pressure.  Dry itching in palms and soles, worse lying down, from rest.

 

References:

  1. Homoeopathic Drug Provings, Central Council for Research in Homoeopathy, 61-65, Institutional Area, Opp. ‘D’ Block, Jankpuri, New Delhi, First Edition, 2005
  2. J. H. Clarke, Dictionary of Practical Materia Medica, Reprint Edition 1992, B. Jain Publishers, New Delhi.
  3. W. Boericke, New Manual of Homoeopathic Materia Medica & Repertory [with Relationship of Remedies], Second Re-Augmented & Revised Edition Based on Ninth Edition, Reprint Edition 2002, B. Jain Publishers, New Delhi.
  4. P. N. Varma, Indu Vaid, Encyclopaedia of Homoeopathic Pharmacopoeia, Updated edition 2007, B. Jain Publishers, New Delhi.
  5. R. Murphy, Homeopathic Remedy Guide, Lotus Health Institute, Stuart, Virginia, United States.
  6. R. Murphy, Homeopathic Clinical Repertory, Lotus Health Institute, Stuart, Virginia, United States.
  7. R. Murphy, Homeopathic Remedy Guide, RadarOpus 1.33 (Homoeopathic Software), Archibel S.A. Rue Fontaine St. Pierre 1E, Zoning Industriel de la Fagne, 5330 Assesse, Belgium.
  8. F. Schroyens, Synthesis Treasure Edition 2009V, RadarOpus 1.33 (Homoeopathic Software), Archibel S.A. Rue Fontaine St. Pierre 1E, Zoning Industriel de la Fagne, 5330 Assesse, Belgium.

 

Mother Tincture info

Syzgium jambolanum

Diabetes mellitus, which is considered to be a silent killer is a disorder of carbohydrate metabolism where the action of insulin secreted by the pancreas is either (a) diminished or (b) altered with, lowered insulin activity.  These are conditions are different from complete lack of endogenous insulin cases (Type I insulin dependant diabetes).  Stimulation or favourable modification of the live secreting cells are observed by use of herbal medicine like Syzgium in Type II diabetes.  Apart from dietary modification, exercise, Syzygium jambolanum or Eugenia jambolana is used in homoeopathy as the most powerful remedy in diabetes mellitus.  No other remedy gives so marked degree of diminution and disappearance of sugar in urine (Dr. S. C. Ghose, Drugs of Hindoosthan).  It is prescribed in mother tincture (1x) in substansive quantities like 20-30 drops three to four times daily for periods ranging from 2-3 months. 

 

The Homoepathic Pharmacopoeial preparation is an alcoholic extract (containing over 80% alcohol) which ensures presence of wide range of phytochemicals which can not be extracted in water alone.  This makes the preparation different from those extracted in water or containing more of water.  The comprehensive effect of all the ingredients cover wide range of symptoms associated in diabetes or in diabetes prone young adults and is effective in mild forms of diabetes.  It has been rated as “very good to control excess blood sugar, glycosuria, diabetes mellitus and diabetes ulcers”.  Compendium of Active Principles / Phytochemicals of Medicinal Plants used in Homoeopathy published by Homoeopathic Pharmacopoeia Laboratory of Govt. of India, (project funded by WHO).

It is used for the following conditions:

?   It lowers blood sugar in Type II diabetes.

?   It is useful in glycosuria. Temporary presence of glucose/ sugar in urine can be reduced.

?   Frequency of urination, dryness of mouth etc. are reduced.

?   It is helpful in diabetic skin conditions and ulcers in diabetics.

?   It normalises digestion, lowers flatulence and favourable influences carbohydrate metabolism.

Note 1: It is important that diet management, exercise, risk of higher glucose levels, the complications are explained to diabetics.

Note 2: Blood glucose / sugar level should be periodically monitored.

Many scientific in vitro and in vivo studies have revealed and confirmed its antihyperglycemic activity and its influence on carbohydrate and lipid metabolisms.

Recommended dose:

Mother tincture: 30 drops in water twice daily for extended period. 

MT/1x tablets: 1-2 tablets 2-3 times a day.

Dose and duration are to be monitored by the physician with reference to the improvements taking place.

References

  1. P. N. Varma, Indu Vaid, Encyclopaedia of Homoeopathic Pharmacopoeia, Updated edition 2007, B. Jain Publishers, New Delhi.
  2. W. Boericke, New Manual of Homoeopathic Materia Medica & Repertory [with Relationship of Remedies], Second Re-Augmented & Revised Edition Based on Ninth Edition, Reprint Edition 2002, B. Jain Publishers, New Delhi.
  3. Acherekar, S., Kaklij, G.S, Pote, M.S., and Kelkar, S.M.: Hypoglycemic activity of Eugenia jambolana and ficus bengalensis: mechanism of action. In vivo, 5, 143–147, 1991.
  4. J. K. Grover, V. Vats and S. S. Rathi, Anti-hyperglycemic effect of Eugenia jambolana andTinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism, Journal of Ethnopharmacology, Volume 73, Issue 3, December 2000, Pages 461-470.
    1. Bhavna Sharma, G. Viswanath, Rajani Salunke and Partha Roy, Effects of flavonoid-rich extract from seeds of Eugenia jambolana (L.) on carbohydrate and lipid metabolism in diabetic mice, Food Chemistry, Volume 110, Issue 3, 1 October 2008, Pages 697-705.

 

 

Lupulus

A native of North America, it is now widely cultivated in North-Western Himalayas.  It is a perennial plant, giving out annular, rough, flexible stems, which twist and twine from left to right about near-by objects, often climbing to a great height.  The leaves are opposite on long petioles, are serrate, prickly, rough, deep-green in colour above; the larger are three to five lobed like cannabis.  It has both male and female plants. It is the flowers of female plants, which are important for medicinal use.  The numerous flowers are axillary.  The scales bear the achenia at the base, where both are covered with numerous yellow shining glands, in mass, appearing as a granular powder.  The ovate strobiles are 1 to 1½ inches long of an aromatic odour and a bitter taste. It is bright, brownish-yellow (becoming yellowish –brown), granular, resinous powder, having an aromatic odour and a bitter taste peculiar to hops.  It has mild sedative action, but is incomparable with mineral acids and metallic salts. 

Boericke recommends this for nervous tremors and delirium of drunkards with giddiness stupefaction, slow pulse, profuse perspiration, spermatorrhoea, and scarlatina like eruptions on face.  Blackwood recommends this for nervousness, irritability, insomnia, delirium, and headache with muscular twitching, sexual debility in make and nocturnal emissions followed by headache.  Synthetic repertory has wide coverage from sadness to alcoholism; delirium, tremens, painful erections but dimished sexual desire; slow pulse and sleeplessness are other symptoms.  Since homoeopathic literature recommends upto 60 drops of mother tincture, it may be interesting to know the action of the medicine and research done on it.  It contains volatile oil (1%) containing humulene, and constituents are lupulin, humulon, lupulon, flavonoids, polyphenolic tannins, oestrogenic substances, asparagus, valerianic acid (responsible for sedation). Collectively the resin in commerce is called lupulin.  There are evidences that it stimulates digestive system, the tincture is sedative, antiseptic, relaxes smooth muscles and is believed to have estrogenic effect.  Hops are key ingredient of Beer and are known to relieve tensions.  Richness of homoeopathic symptom coverage along with knowledge on the products makes it a drug to remember in much stress related problems.

Recommended dose: (1) Mother tincture to 3x; locally in painful cancers (Boericke).

          (2) Mother tincture 1 to 60 drops  (Blackwood)

References

  1. J. H. Clarke, Dictionary of Practical Materia Medica, Reprint Edition 1992, B. Jain Publishers, New Delhi.
  2. Homoeopathic Pharmacopoeia of the United States, Southeastern, PA, Homeopathic Pharmacopeia Convention of the United States (available by subscription at https://www.hpus.com/).
  3. Sean C Sweetman, Martindale: The Complete Drug Reference, Pharmaceutical Press, London, Thirty Seventh Edition, 2011.
  4. W. Boericke, New Manual of Homoeopathic Materia Medica & Repertory [with Relationship of Remedies], Second Re-Augmented & Revised Edition Based on Ninth Edition, Reprint Edition 2002, B. Jain Publishers, New Delhi.
  5. A. L. Blackwood, A Manual of Materia Medica, Therapeutics and Pharmacology, Reprint Edition 1995, B. Jain Publishers, New Delhi.
  6. F. Schroyens, Synthesis Treasure Edition 2009V, RadarOpus 1.33 (Homoeopathic Software), Archibel S.A. Rue Fontaine St. Pierre 1E, Zoning Industriel de la Fagne, 5330 Assesse, Belgium.
  7. Andrew Chevallier, The Encyclopedia of Medicinal Plants, 1st Edition, 1996, Dorling Kindersley, London.

 

Product watch

Dr. Willmar Schwabe’s Alfalfa Tonic®

INTRODUCTION

Dr. Willmar Schwabe’s Alfalfa Tonic® provides natural aminoacids, minerals and potent herbal ingredients, so as to stimulate general physical and mental activity and promote well-being. It also supports the regenerative process during and after diseases as well as in all stages.

 

Dr. Willmar Schwabe’s Alfalfa Tonic® eliminates symptoms of fatigue and leads to an increase in appetite, while stomach-complaints and improper digestive functions are improved simultaneously. General nervous tension, stress and irritability are soon calmed. Remarkable improvement in cases of anaemia has been observed after prolonged medication in juveniles.

 

Indications:           Health Tonic for both sexes of all ages for convalescence,  general weakness, lethargy, lack of appetite, stress, tension and sleep disorders.

Composition:

Acidum phosphoricum 2x                                    5.0%

Alfalfa Q                                                                                   1.0%

Avena sativa Q                       5.0%                 

China Q                               0.25%

Cinnamomum Q                              0.5%

Hydrastis canadensis Q                 0.5%

Kalium arsenicosum 6x                  1.0%

Nux vomica 2x                         0.25%

Excipients q.s.

Alcohol content v/v                                  11.9%

                                                                                               

Proven indications of the individual ingredients within the claimed sphere of action of the product :

 

Acidum phosphoricum : Indicated for nervous exhaustion, mental and physical debility in growing and over taxed persons. Useful for ailments due to loss of vital fluids, vertigo, pain in eyeballs, frequent urination and weakness.

 

Alfalfa (Medicago sativa) : It favourably influences nutrition by toning up the appetite and digestion, improves vigour and is indicated for neurasthenia, nervousness and insomnia. It increases quality and quantity of milk in lactating mothers.

 

Avena sativa : Tonic for debility after exhausting diseases, and general fatigue. It is reputed to have sedative activity and is claimed to be of value in drug-dependance.

 

China (Cinchona officinalis) : It is a well verified remedy for debility, irritability, throbbing headache, flatulence, belching due to organic dysfunction, exhausted feeling due to loss of vital fluids, anorexia (loss of appetite) etc.

 

Cinnamomum : It is useful in minor haemorrhages, flatulence in weak persons with languid circulation.

 

Hydrastis : Indicated for easily tiring persons with debility and catarrhal symptoms and weightloss. Weak muscular power, poor digestion, lumbago and constipation, especially suitable for the elderly.

 

Kalium arsenicosum : Recommended for chronic anaemia, inbuilt nervousness and restlessness. The person tends to be restless, nervous and  anaemic.

 

Nux vomica : It is one of the best remedy for balancing and bringing equilibrium of different functions. Dysfunction due to over indulgence in sex, fat foods, stimulants, alcohol resulting irritability, indigestion, ineffectual evacuation and lethargic feeling resembling great debility. It overcomes cramps and neuralgias.

 

Dosage : Adults one tablespoon, children one teaspoon, one hour before meals, three times a day.  If complaints are not relieved, consult a  specialist.

 

Side effects :  No side effects of Dr. Willmar Schwabe’s Alfalfa Tonic® are known.

 

Advantages : Improved processing technology helps retain the natural ingredients of the herbs at its optimum levels. It is a non-toxic preparation and can be safely taken by different age groups. It has a corrective action on various body functions and can be used freely as general tonic.

 

Contra-indications :  No contra-indications for the use of Dr. Willmar Schwabe’s Alfalfa Tonic®  are known.

 

Interactions :  No interactions between Dr. Willmar Schwabe’s Alfalfa Tonic®  and other products are known.

 

Presentation : 100 ml  and 500 ml  bottles

 

Essentia Aurea Gold - Drops

 

Introduction

Ischaemic heart disease secondary to atherosclerosis of the coronary arteries remains a leading cause of morbidity and mortality. Risk factors for the development of coronary artery atherosclerosis include a family history of premature coronary artery disease, cigarette smoking, hypercholesteraemia, hypertension, and diabetes mellitus. Obesity, physical inactivity, and stress may play a lesser role. Coronary artery disease may be clinically silent but is more frequently associated with symptoms (e.g., myocardial infarction, angina pectoris, sudden death).

 

Angina pectoris is the chest discomfort associated with myocardial ischaemia that occurs when myocardial oxygen demand exceeds supply. Angina is typically described as a retrosternal pain, discomfort, heaviness, or pressure radiating to the neck, jaw, shoulders, or arms. It is usually precipitated by exertion. Associated symptoms include dyspnoea, diaphoresis, nausea, vomiting, and occasionally palpitations. Treatment is directed toward improving myocardial oxygen supply, reducing myocardial oxygen demand, and treating precipitating factors or concurrent disorders that may exacerbate ischaemia.

 

Indications: Symptoms of mild forms of cardiac weakness, hypertension, stenocardia, or dysrhythmia (cardiotonic action).

 

Composition

Crataegus oxyacantha Q                                  40%

Aurum muriaticum 4x                                          10%

Convallaria majalis 1x                                        10%

Ignatia amara 4x                                                 10%

Veratrum album   3x                                             10%   

Arnica Montana Q                                               0.5%

Excipients q. s.

Alcohol content:                                                  58% v/v

 

 

Proven indications of the individual ingredients in the sphere of claimed action:

 

Crataegus oxyacantha acts on heart muscle as a heart tonic. It lowers the pulse, air hunger, and reduces blood pressure. It has an effect on extreme dyspnoea on minimal exertion, pain in the heart region and under the left clavicle, cold extremities, blueness of fingers, irregular pulse. It helps in cases of chronic heart diseases and arteriosclerosis.

 

Aurum muriaticum is indicated for cardiac symptoms of varied nature, arteriosclerosis, valvular lesions and hypertension. It acts on palpitation and tachyarrhythmia.

 

Convallaria majalis is a heart remedy, which increases the heart’s action and renders it more regular. It is used when the ventricles are over distended or dilated and venous stasis is marked. It is indicated for dyspnoea, dropsy, tobacco heart, orthopnoea, angina pectoris, and tachyarrhythmia. It also acts on palpitation.

 

Ignatia amara is useful in patients of sensitive excitable nature, and helps overcome grief and worry. It is indicated for depression, nervousness, trembling, sleep disorders, constrictive feeling in throat and chest.

 

Veratrum album is indicated for collapse, weakness and extreme coldness. It covers cold extremities, cold sweat on forehead, paleness, feeble pulse, and palpitation with anxiety and rapid audible respiration.

 

Arnica montana affects the blood and vascular system. Symptoms occur after any trauma or overuse. It is indicated for cardiac dropsy with dyspnoea, angina pectoris, feeble and irregular pulse, cardiac asthma.

 

Directions for use:

Dosage: Unless otherwise prescribed, Essentia Aurea should be applied as follows:

10-20 drops should be taken 3 times a day.

Note: For treatment during pregnancy and lactation, and for patients with serious liver or alcohol problems, in particular, please note that this product contains alcohol.

Side effects: No side effects of Essentia Aurea are known.

Contra-indications: Essentia Aurea is not indicated for children.

Interactions: No interactions between Essentia Aurea and other products are known.

Presentation: Bottle of 30 ml.

 

Research news                  

Protective effect of Gymnema sylvestre L. against advanced glycation end-product, sorbitol accumulation and aldose reductase activity in Homoeopathic Formulation

Oxidative stress ensues due to the imbalance between the production and elimination of reactive oxygen species. Chronic hyperglycemia along with oxidative stress plays major role in aggravation of chronic disorders such as diabetes and its related complications. This study was designed to evaluate the protective effect of Gymnema sylvestre L. against oxidative stress.

Potencies of G. Sylvestre were procured from Dr. Willmar Schwabe India Pvt. Ltd. In vitro antioxidative potential of G. sylvestre was evaluated by employing various in vitro antioxidant methods.

The total phenol content was found to be 2124, 998 and 546 mg/g Gallic Acid Equivalents in Mother tincture, 6C and 30C of G. sylvestre and total antioxidant capacity was found to be 2940,802 and 559 ?M/g ascorbic acid equivalents respectively. Mother tincture, 6C and 30C of G. sylvestre were found to have strong reducing power, 2,2-diphenyl-1-picrylhydrazyl radical, hydrogen peroxide, nitric oxide and superoxide radical scavenging activity. Percentage inhibition of advanced glycation end-products formation by Mother tincture, 6C and 30C of G. sylvestre (10-50 ?l) was found to be 38.66 to 95.80%, 30.93 to 81.48% and 31.34 to 60.92% respectively. Mother tincture, 6C and 30C of G. sylvestre showed an inhibitory effect against sorbitol accumulation with inhibitory concentration (IC50) value 27.55 ?l, 197.96 ?l and 1.009 ml respectively whereas in aldose reductase inhibition assay, the IC50value of 28.10 ?l, 159.71 ?l and 0.82 ml respectively. These results suggested that Homoeopathic preparations of G. Sylvestre had potent antioxidant and antiglycation activity.

This study was financially assisted by the Ministry of AYUSH, Government of India.

Reference: Kishore L, Singh R. Protective effect of Gymnema sylvestre L. against advanced glycation end-product, sorbitol accumulation and aldose reductase activity in Homoeopathic Formulation. Indian J Res Homoeopathy [serial online] 2015 [cited 2016 Feb 10];9:240-8. Available from: https://www.ijrh.org/text.asp?2015/9/4/240/172866

 

Homoeopathic drug standardization through biological evaluations: An untrodden avenue

It is a review article linking recent advancements in instrumentation and quality analysis, and homoeopathic standardization. There is a dearth of chemico-analytical or instrumental methods for standardization and quality control of higher dilutions of homoeopathic drugs. This review highlights the challenges in standardization of anti-inflammatory homoeopathic drugs and suggests a battery of biological assays for their standardization.

The authors have retrieved a total 57 scientific reports from the experimental studies and scientific reviews published between January 1999 and June 2014 related to anti-inflammatory homoeopathic drugs and their high dilutions. These comprised of 18 reports on preclinical evaluation, 15 on source materials, 9 on isolated constituents and 15 studies on in-vitro experiments. Few recent citations which supported the initial studies were added later during the compilation of the manuscript.

Standardization and quality control of homoeopathic mother tinctures and high dilutions warrants an urgent attention. As biological activities are observed to be attributed to the high dilutions which are practically devoid of active ingredients, their standardization may be done through the suggested battery of biological investigations. It is suggested by the authors that the current methods of standardization of homoeopathic drugs need to be upgraded to include sensitive, reproducible and relevant biological assays so that the end users are assured of the quality, efficacy, and safety of homoeopathic dilutions.

Reference: Kardile MV, Patil C, Haidar A, Mahajan UB, Goyal S. Homoeopathic drug standardization through biological evaluations: An untrodden avenue. Int J High Dilution Res. 2015;14(4):16-37

Immunological models in high dilution research following M Bastide

In 1994, Madeleine Bastide described experimental models in immunology that were used during the 1980s to investigate high dilution effects on several biological systems. She classified the available papers in four categories: High dilutions of antigens; High dilutions of thymus, bursa and other hormones; High dilutions of cytokines; Immunopharmacological activity of silica. The studies about high dilutions of antigens were not continued after this period, but gave rise to a long process of a series of in vitro models on antigens and histamine dilutions, that led to the demonstration of the biological modulation effects of these preparations on basophil degranulation. During this process, a multi-centre study was performed, with a high degree of reproducibility among different independent laboratories. The studies about high diluted cytokines, thymulin and other hormones opened a new line of scientific investigation, about the regulatory properties of endogenous substances prepared according to homoeopathic methods. The most frequently studied substance, thymulin, when administered to mice at 5cH potency, is able to improve the activity of phagocytes in different experimental situations, such as viral, bacterial and parasitic infections. The immunopharmacological activity of silica was demonstrated, at that time, as an in vivo illustration of the homoeopathic 'similia principle'. More recently, studies on silica have assumed another focus: the putative role of silica as active contaminant present in high dilutions. This paper presents a follow-up summary on these items, considering the evolution of discoveries from 1994 to 2014.

Referances: Bonamin LV, Bellavite P. Immunological models in high dilution research following M Bastide. Homeopathy. 2015 Oct;104(4):263-8. doi: 10.1016/j.homp.2015.08.004. Epub 2015 Sep 14.

 

 

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