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Currently a multicentric, three-armed, randomised clinical trial had been done to assess the effectiveness of constitutional homoeopathic remedy (HC) and organ remedy along with constitutional remedy (HCOM) alongside placebo in benign prostatic hyperplasia using International Prostate Symptom Score (IPSS), ultrasonographic changes in prostate volume, post-void residual urine, uroflowmetry and in WHO Quality of Life (QOL)-BREF. Patients were included as per the pre-defined inclusion and exclusion criteria in five centers and divided into randomized three group in 2:2:1 ratio and followed-up for 3 months. The statistical analysis was done with modified intention-to-treat principle (mITT). 461 patients screened among 254 patients were enrolled in the study whereas 241 patients were analysed as per mITT.  QOL and IPSS due to urinary symptoms had been reported positively in all three groups; however HC group reported more significant changes as compared to other two groups. There was no difference between HC and HCOM groups and they were equally effective in terms of managing lower urinary tract symptoms due to BPH. WHOQOL-BREF have shown positive trend in respect to psychological, social and environmental domains. From the study it is concluded that statistical significance was found in the IPSS in all the three groups but only in HC and not in any of the objective parameters.


Bindu Sharma, Pritha Mehra, Praveen Oberai, Varanasi Roja, G. R. C. Reddy, DD Arya, B. S. J. Raja Kumar, PG Mohanan, Akshaya Kumar Prusty, Maya Padmanabhan, Raj K Manchanda. Homoeopathic treatment for lower urinary tract symptoms in men with benign prostatic hyperplasia: An open label randomised multicentric placebo-controlled clinical trial, Indian Journal of Research in Homoeopathy, Year: 2018, Volume: 12, Issue: 3, Page: 113-124.

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