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Hertone

Introduction

Hertone is a new product developed by Schwabe. Clinical problems of female sex are varied. Scientist has taken care to develop a non-toxic formulation with wide coverage. Inputs for need of such a product covered from simple menstrual disturbances and dysmenorrhoea to complicated conditions like ovarian cyst (also called as polycystic ovarian disease/syndrome or PCOD/PCOS) and uterine fibroids. Though genetics plays a role in developing these problems, modern researchers link it to the badly behaved female hormones oestrogen, progesterone and others. , Experts in the field explain how our modern day lifestyle affects these hormones and end up in many of these problems. As a result, symptoms of imbalanced hormones well before developing any of these specific “disorder” are felt. Subsequently these problems develop after sometime. Initially there may be slight disturbance in the menstrual cycle and nature of pain during menses. These may be associated with general symptoms like sleeplessness, pedal oedema, poor appetite, weight gain, etc. Over a period of time these develop as disorders of female reproductive system. Hertone is a product which covers different stages of such disorders.

The disorders of female reproductive system have been grouped (a) menstrual disturbances, (b) vaginal discharges, and (c) growths & cysts. Hertone is indicated in menstrual disturbances including amenorrhoea (secondary), menorrhagia, metrorrhagia and dysmenorrhoea. Abnormal vaginal discharge such as leucorrhoea of different types is covered by Hertone. It also covers uterine fibroid and ovarian cyst with intermittent or continuous pain which may be mild to severe intensity in lower abdomen. Pain in uterine fibroid is more often generalized. Pain of ovarian origin is usually felt at ovarian regions or sides (iliac fossae). The product covers endometriosis, which is an abnormal endometrial growth on ovary and tissues lining the pelvis.

The formulation strengthens the female reproductive organs. Hertone has 6 ingredients which are known for their role in female reproductive system. Apart from their traditional use, the modern research on them recommends their use. It is used for functional tone up of female reproductive system. The ingredients act as uterotonic, anti-inflammatory, emmenagogue, estrogenic, anti-spasmodic, androgenic, uterosedative and others.

Composition:

Each 100ml contains:

Abroma radix Ø HPI                                                            5%          v/v

Aletris farinosa Ø HPUS                                                   5%          v/v

Caulophyllum thalictroides Ø HPI                                   1%          v/v

Cimicifuga racemosa Ø HPI                                              1%          v/v

Helonias dioica Ø HPI                                                        3%          v/v

Janosia ashoka Ø HPI                                                      5%          v/v

Alcohol content                                                                    11.5%    v/v

Excipients:                                                                            QS

Indications: Uterine tonic. Covers amenorrhoea, menstrual irregularities such as menorrhagia, dysmenorrhoea. It is used for leucorrhoea, ovarian cyst, uterine fibroid, and endometriosis. As a supportive therapy, it is also used in related water retention, insomnia, debility, anxiety, rectal distress, constipation, etc. and cases of infertility. Symptoms of premenstrual syndrome (PMS) like mood swings, tender breasts, food cravings, fatigue, irritability and depression are also covered.

Proven indications of the individual ingredients in the sphere of claimed action:

Abroma radix Q: It is an uterine tonic and emmenagogue, given in congestive and neuralgic dysmenorrhea (as a sedative), amenorrhoea and leucorrhoea. It is useful in albuminurea, sleeplessness and debility. It is reported to be useful in sterility and as anabortifacient agent.

Aletris farinosa Q: This remedy has special affinity towards female organism. Its oestrogenic action is well proved. Premature and profuse menses with labour like pain. Useful for dysmenorrhea and irregular threatened abortions. It is one of the important remedies for infertility. It is used as a general tonic due to its action like a sedative to promote relaxation. It covers debility, joint and muscle pains during menses, prolapsus, leucorrhoea, fluid retention, colic, stomach upset, constipation, rectal distress, diarrhoea, etc. Also used in anaemia in young girls.

Caulophyllum thalictroides Q: It acts like a tonic. This agent acts upon the uterus as an emmenagogue and paturifacient (an agent that induces the contractions of labor at childbirth). Hence it is used during labour, when the pains are deficient and the patient is exhausted and fretful. It also acts upon the muscles & small joints, and used in similar kind of pain during menses, menopause, etc. Useful in chronic acric leucorrhoea and associated exhaustion. It is reported to control the haemorrhage that follows hasty labors, and passive haemorrhage that accompanies abortions. Possess antispasmodic, anti-inflammatory, anti-rheumatic and diuretic activities.

Cimicifuga racemosa Q: It acts upon the uterus and ovaries. Especially useful in ovarian irritation, uterine cramps and heavy limbs. Covers muscular and crampy pains, primarily of neurotic origin. Pain in ovarian region; shoots upward and down anterior surface of thighs. Pain immediately before menses. Used in dysmenorrhoea with backache which occurs in people with irregular menses. Pain across pelvis, from hip to hip. Infra-mammary pains worse, left side. Facial blemishes (mark or spot affecting appearance) in young women. It is given since the fifth month of pregnancy to make the muscles of parturition relaxed.

Recent clinical evidence supports the efficacy and safety of this drug for symptoms of premenstrual tension, menopause and other gynecological problems, complications associated with childbirth. 

Helonias dioica Q: Its chief action is on female reproductive organs, especially to improve the tone of the reproductive organs. , It has also been used traditionally for dysmenorrhoea, amenorrhoea, leucorrhoea, prolapse with disordered menstruation and to improve libido.  It is regarded primarily as a uterine tonic, but also its action on the ovaries is well-known. Hence it is used in pelvic inflammation and to improve fertility. , It also covers prolapse of uterus (due to weakness) and other malposition of the womb. Used in cases of ovarian cysts, menses often suppressed and the kidneys are congested. Considered useful during menopause. It is reported to be useful to prevent miscarriages.  Modern literature also supports its use to treat different problems as menstrual problems, pregnancy complaints, fertility issues, ovarian cysts and diuretic.  Results of a very recent study suggest that this drug possesses antioxidative potentials. 

Janosia ashoka Q: It has extensive sphere of action on female organs. It is used in cases of amenorrhoea for regulating rhythm and flow, and metrorrhagia. Research has shown that it possesses oxytocic, stimulant, spasmogenic action on uterus. Its phytoconstituent saracin is seen as immunomodulator, and the drug as a whole good for female reproductive system. Recent studies have found it to possess antimenorrhagic, anti-inflammatory, antioxytocic, analgesic and uterine tonic activities.

Dosage: Unless otherwise prescribed, Hertone should be taken as follows: 1-2 teaspoon 2-3 times daily.

Side effects: No side effect of Hertone , are known.

Contra-indications: No contra-indications for the use of Hertone , are known.

Interactions:  No interactions between Hertone , and other products are known.

Presentation: Bottle of 100 ml.

 

References:

  1. Anne Zimmermann; David Bernuit; Christoph Gerlinger; Matthias Schaefers; Katharina Geppert, Prevalence, Symptoms and Management of Uterine Fibroid, BMC Womens Health. 2012;12(6)
  2. Rein MS, Barbieri RL, Friedman AJ, Progesterone: a critical role in the pathogenesis of uterine myomas. Am J Obstet Gynecol. 1995 Jan; 172(1 Pt 1):14-8.
  3. Department of Health, New York State, Uterine Fibroids. Retrived from: https://www.health.ny.gov/community/adults/women/uterine_fibroids. Accessed on: 12-May-2016
  4. Catherine, Estrogen Dominance: The Hormonal Imbalance That Causes Edema, Weight Gain, Infertility, Low Thyroid, Varicose Veins and More! Retrived from: http://butternutrition.com/estrogen-dominance-hormonal-imbalance. Accessed on: 12-May-2016
  5. Dr. Mercola, What is Really Interfering with Women’s Hormones? Retrived from: http://articles.mercola.com/sites/articles/archive/2009/11/21/what-is-really-interfering-with-womens-hormones.aspx. Accessed on: 12-May-2016
  6. Lindsay Boyers, Natalie Butler, How Your Diet Affects Your Hormones During Menopause. Retrived from: http://www.healthline.com/health/menopause/diet-hormones. Accessed on: 12-May-2016
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  14. Information on Aletris. Retrived from: http://www.webmd.com/vitamins-supplements/ingredientmono-605-aletris.aspx. Accessed on: 13-May-2016
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  17. reprinted Eclectic Medical Publications, Portland, 1983.
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  25. Debrup Chakraborty, Asmita Samadder, Suman Dutta and Anisur Rahman Khuda-Bukhsh, Antihyperglycemic potentials of a threatened plant, Helonias dioica: antioxidative stress responses and the signaling cascade, Exp Biol Med, January 2012 vol. 237 no. 1 64-76
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