Schwabe News Volume 3 | Issue 5 & 6| October & December 2012
It is also known by the name Janosia asoca or Saraca indica. It is of the family Leguminosae and is an Indian tree 7-10 m. high with glabrous branches, 15-20 cm long glabrous leaves with 4-6 pairs of leaflets. The tincture is made from the bark and is a proved medicine (1). The affinity of this drug is female reproductive organs. The mother tincture is generally used for delayed and irregular menses, menstrual colic, arnemorrhoea, pain in ovaries before flow, menorrhagia, irritable bladder with other symptoms like unilateral headache, reflex uterine, congestive headache, better open air and by free flow. Desire for sweets, also acid things, thirsty, excessive nausea, obstinate constipation, haemorrhoids are also covered (2,3).
It has many phytochemicals which have been extensively worked pharmacologically and clinically. Ketosterol, a glycosidal fraction, a saponin and an organic calcium compound are found from the whole plant. Ketosterol and the calcium salts are important in the treatment of menorrhagia (4,5). 11-Deoxyprocyanidin B-isolated from root bark (-) epicatechin and procyanidin B2 and other phytochemical have also been isolated. A phenolic glycoside showed highly potent and specific oxytocic activity in vitro and in vivo on uteri of rat and isolated human myometrial strips and fallopian tube. It was active in remarkably low concentrations and nontoxic to animals upto 250 mg/kg (6). Two crude glycosides isolated from bark have exhibited uterine spasmogenic activity and both showed significant stimulant action on isolated uteri of rat, guinea pig, rabbit, dog and human; pure phenolic glycoside P2 was highly potent and showed consistent oxytocic activity (7).
Recommended dose: 10-20 drops 2-3 times a day, depending upon the case
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